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Science · Life Science
Genetic Engineering and Gene-Editing Lab
Students design a CRISPR guide, model DNA repair, build and check a plasmid on a gel, and analyze transformation data.
Grades 11–12Virtual lab · 5 stations1 student per deviceNo student loginsWorks offline
Try it free: the demo opens the Start page and Station 1 right in your browser. No sign-up needed.
Virtual labs are sold separately and aren’t part of the All-Access licenses.

Grade level
- Grades 11–12: Conceptual biotechnology models using real base-pairing, codon and fragment-size rules
What students practice
CRISPR guide RNA and PAM sites, DNA repair by NHEJ and HDR, frameshift mutations, restriction enzymes and sticky ends, gel electrophoresis standard curves, transformation efficiency
Standards
NGSS: HS-ETS1-3 · HS-LS1-1 · HS-LS3-1 · HS-LS3-2
More games for these standards and topics
How it works
- Open the game file in any web browser: Chromebooks, laptops or your smartboard. No accounts, no student logins and no internet needed once it's downloaded.
- Each student types their name on the Start page, then works through the stations in order. Each station has a prediction, a hands-on activity, a data table or log that fills in as they work and a check question.
- Students finish with a printable lab report (print or save as PDF). The Teacher Notes include the standards, a full answer key and a reset button for shared devices.
- Each purchase includes the lab file and a one-page Quick Start guide.
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